🧬Biology
Genetics & Heredity
Mendelian genetics, chromosomal theory, sex determination, mutations, and DNA replication.
Class 11Class 12
What You Will Learn in Genetics & Heredity
Genetics is the study of heredity — how traits are passed from parents to offspring through genes encoded in DNA.
- Mendel's laws: Law of Segregation (alleles separate in gametes) and Law of Independent Assortment (genes on different chromosomes segregate independently).
- Monohybrid cross: Tt × Tt → 1 TT : 2 Tt : 1 tt (genotype 1:2:1; phenotype 3:1).
- Dihybrid cross: TtRr × TtRr → 9:3:3:1 phenotypic ratio.
- DNA structure: double helix, antiparallel strands, A-T and G-C base pairs (Watson-Crick).
- Mutations: point mutations (substitution, insertion, deletion), chromosomal mutations; cause genetic disorders.
- Sex determination: XX female, XY male; sex-linked traits (haemophilia, colour blindness) on X chromosome.
Example
Mendel's pea plant experiments (1865) revealed dominant/recessive inheritance using tall (T) and short (t) traits.
Expected Exam Questions — Genetics & Heredity
Q1.In a monohybrid cross Tt × Tt, what is the phenotypic and genotypic ratio?
Answer: Phenotypic ratio: 3 Tall : 1 short (3:1). Genotypic ratio: 1 TT : 2 Tt : 1 tt (1:2:1). T is dominant (tall), t is recessive (short). The F₂ generation from selfing Tt (F₁) gives these ratios.
Q2.What is co-dominance? Give an example.
Answer: Co-dominance: both alleles are equally expressed in a heterozygote — neither is dominant. Example: ABO blood group (IAIb = AB blood type, both A and B antigens expressed). Sickle cell: HbAHbS has both normal and sickle-shaped cells.
Q3.Why is colour blindness more common in males than females?
Answer: Colour blindness is X-linked recessive. Males (XY) have only one X — if it carries the allele (Xᶜ Y), they are colour blind. Females (XX) need both X's to carry the recessive allele (XᶜXᶜ) to be colour blind; one normal X is enough to be a carrier. Females can be carriers (XᶜX) without showing the trait.
🔘 MCQ Practice — Genetics & Heredity
MCQ 1.What is the phenotypic ratio in a dihybrid cross?
A. 1:2:1
B. 3:1
C. 9:3:3:1 ✓
D. 1:1:1:1
✓ Correct Answer: 9:3:3:1
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